AE-848/42025420 structure

AE-848/42025420

TL;DR: AE-848/42025420 (CAS 524002-77-5) is a chemical compound with molecular formula C27H27N3O4 and molecular weight 457.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-pyridin-4-yl-9-(3,4,5-trimethoxyphenyl)-5,6,8,9,10,11-hexahydrobenzo[b][1,4]benzodiazepin-7-one

Also Known As: AE-848/42025420, A3193/0135326, 6-pyridin-4-yl-9-(3,4,5-trimethoxyphenyl)-5,6,8,9,10,11-hexahydrobenzo[b][1,4]benzodiazepin-7-one, 11-(pyridin-4-yl)-3-(3,4,5-trimethoxyphenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, 11-(4-pyridinyl)-3-(3,4,5-trimethoxyphenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

CAS: 524002-77-5
Molecular Formula C27H27N3O4
Molecular Weight 457.20 g/mol
LogP 5.0869
Topological Polar Surface Area 81.71 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 457.20016
Heavy Atoms 34
Complexity 1230.735

Chemical Identifiers

CAS Number 524002-77-5
SMILES COC1=CC(=CC(=C1OC)OC)C2CC3=C(C(NC4=CC=CC=C4N3)C5=CC=NC=C5)C(=O)C2

Product Overview

AE-848/42025420 (CAS 524002-77-5), with molecular formula C27H27N3O4 and molecular weight 457.20 g/mol. IUPAC: 6-pyridin-4-yl-9-(3,4,5-trimethoxyphenyl)-5,6,8,9,10,11-hexahydrobenzo[b][1,4]benzodiazepin-7-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AE-848/42025420

XLogP
5.0869
TPSA (Topological Polar Surface Area)
81.71
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
34
Complexity
1230.735
Exact Mass
457.20016
Monoisotopic Mass
457.20016
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AE-848/42025420

The XLogP value of 5.0869 indicates that AE-848/42025420 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.71 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/42025420. Following Lipinski's Rule of Five, AE-848/42025420 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AE-848/42025420?

The CAS number of AE-848/42025420 is 524002-77-5.

What is the molecular formula of AE-848/42025420?

The molecular formula of AE-848/42025420 is C27H27N3O4.

What is the molecular weight of AE-848/42025420?

The molecular weight of AE-848/42025420 is 457.20 g/mol.

Where can I buy AE-848/42025420?

You can request a quote for AE-848/42025420 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AE-848/42025420?

Yes, KEHONG BIO provides custom synthesis services for AE-848/42025420 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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