![6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one structure](/static/products/523/523990-89-8.png)
6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one
TL;DR: 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one (CAS 523990-89-8) is a chemical compound with molecular formula C22H16ClNOS and molecular weight 377.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-3-(4-methylphenyl)sulfanyl-4-phenyl-1H-quinolin-2-one
Also Known As: 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one, 6-chloro-4-phenyl-3-(p-tolylthio)quinolin-2(1H)-one, 6-chloro-3-(4-methylphenylthio)-4-phenylhydroquinolin-2-one, 6-chloro-3-[(4-methylphenyl)sulfanyl]-4-phenylquinolin-2-ol, 6-chloro-3-(4-methylphenyl)sulfanyl-4-phenyl-1H-quinolin-2-one
| Molecular Formula | C22H16ClNOS |
|---|---|
| Molecular Weight | 377.06 g/mol |
| LogP | 6.30812 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 377.06412 |
| Heavy Atoms | 26 |
| Complexity | 1134.6082 |
Chemical Identifiers
| CAS Number | 523990-89-8 |
|---|---|
| SMILES | CC1=CC=C(C=C1)SC2=C(C3=C(C=CC(=C3)Cl)NC2=O)C4=CC=CC=C4 |
Product Overview
6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one (CAS 523990-89-8), with molecular formula C22H16ClNOS and molecular weight 377.06 g/mol. IUPAC: 6-chloro-3-(4-methylphenyl)sulfanyl-4-phenyl-1H-quinolin-2-one.
Chemical Property Profile of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one
Property Insights of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one
The XLogP value of 6.30812 indicates that 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.86 Ų, 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one?
The CAS number of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one is 523990-89-8.
What is the molecular formula of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one?
The molecular formula of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one is C22H16ClNOS.
What is the molecular weight of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one?
The molecular weight of 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one is 377.06 g/mol.
Where can I buy 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one?
You can request a quote for 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-3-[(4-methylphenyl)thio]-4-phenylquinolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.