Acetaminophen mercapturate structure

Acetaminophen mercapturate

TL;DR: Acetaminophen mercapturate (CAS 52372-86-8) is a chemical compound with molecular formula C13H16N2O5S and molecular weight 312.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2R)-2-acetamido-3-(5-acetamido-2-hydroxyphenyl)sulfanylpropanoic acid

Also Known As: Acetaminophen mercapturate, Paracetamol mercapturate, Acetaminophen-2-mercapturate, 3-(N-acetyl-L-cystein-S-yl) acetaminophen, acetaminophen mercapturic acid

CAS: 52372-86-8
Molecular Formula C13H16N2O5S
Molecular Weight 312.08 g/mol
LogP 0.2
Topological Polar Surface Area 141.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 312.078
Heavy Atoms 21
Complexity 404.0

Chemical Identifiers

CAS Number 52372-86-8
SMILES CC(=O)NC1=CC(=C(C=C1)O)SC[C@@H](C(=O)O)NC(=O)C
InChIKey DVPRQNKJGQEICH-JTQLQIEISA-N

Product Overview

Acetaminophen mercapturate (CAS 52372-86-8), with molecular formula C13H16N2O5S and molecular weight 312.08 g/mol. IUPAC: (2R)-2-acetamido-3-(5-acetamido-2-hydroxyphenyl)sulfanylpropanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Acetaminophen mercapturate

XLogP
0.2
TPSA (Topological Polar Surface Area)
141.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
21
Complexity
404.0
Exact Mass
312.078
Monoisotopic Mass
312.078
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Acetaminophen mercapturate

The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Acetaminophen mercapturate. The TPSA of 141.0 Ų indicates high polarity, suggesting Acetaminophen mercapturate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Acetaminophen mercapturate has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Acetaminophen mercapturate?

The CAS number of Acetaminophen mercapturate is 52372-86-8.

What is the molecular formula of Acetaminophen mercapturate?

The molecular formula of Acetaminophen mercapturate is C13H16N2O5S.

What is the molecular weight of Acetaminophen mercapturate?

The molecular weight of Acetaminophen mercapturate is 312.08 g/mol.

Where can I buy Acetaminophen mercapturate?

You can request a quote for Acetaminophen mercapturate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Acetaminophen mercapturate?

Yes, KEHONG BIO provides custom synthesis services for Acetaminophen mercapturate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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