Colchicine, 1-demethyl-
TL;DR: Colchicine, 1-demethyl- (CAS 5232-73-5) is a chemical compound with molecular formula C21H23NO6 and molecular weight 385.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(1-hydroxy-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Also Known As: 1-Demethylcolchicine, Colchicine, 1-demethyl-, N-(1-Hydroxy-2,3,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide #, N-(1-hydroxy-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide, N-[(7S)-1-hydroxy-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
| Molecular Formula | C21H23NO6 |
|---|---|
| Molecular Weight | 385.15 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 94.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 385.15253 |
| Heavy Atoms | 28 |
| Complexity | 724.0 |
Chemical Identifiers
| CAS Number | 5232-73-5 |
|---|---|
| SMILES | CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)O)OC)OC |
| InChIKey | IGLDJTYPTSDFND-UHFFFAOYSA-N |
Product Overview
Colchicine, 1-demethyl- (CAS 5232-73-5), with molecular formula C21H23NO6 and molecular weight 385.15 g/mol. IUPAC: N-(1-hydroxy-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide.
Chemical Property Profile of Colchicine, 1-demethyl-
Property Insights of Colchicine, 1-demethyl-
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicine, 1-demethyl-. The TPSA of 94.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, 1-demethyl-. Following Lipinski's Rule of Five, Colchicine, 1-demethyl- has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, 1-demethyl-?
The CAS number of Colchicine, 1-demethyl- is 5232-73-5.
What is the molecular formula of Colchicine, 1-demethyl-?
The molecular formula of Colchicine, 1-demethyl- is C21H23NO6.
What is the molecular weight of Colchicine, 1-demethyl-?
The molecular weight of Colchicine, 1-demethyl- is 385.15 g/mol.
Where can I buy Colchicine, 1-demethyl-?
You can request a quote for Colchicine, 1-demethyl- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, 1-demethyl-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, 1-demethyl- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.