Enpiroline
TL;DR: Enpiroline (CAS 52300-95-5) is a chemical compound with molecular formula C19H18F6N2O and molecular weight 404.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(R)-piperidin-2-yl-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]-4-pyridinyl]methanol
Also Known As: Enpiroline, J1.336.370F, (R)-alpha-(2-Piperidinyl)-2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]-4-pyridinemethanol, (R)-piperidin-2-yl-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]pyridin-4-yl]methanol, (Piperidin-2-yl){2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]pyridin-4-yl}methanol
| Molecular Formula | C19H18F6N2O |
|---|---|
| Molecular Weight | 404.13 g/mol |
| LogP | 4.9617 |
| Topological Polar Surface Area | 45.15 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 404.13232 |
| Heavy Atoms | 28 |
| Complexity | 810.65405 |
Chemical Identifiers
| CAS Number | 52300-95-5 |
|---|---|
| SMILES | C1CCNC(C1)[C@@H](C2=CC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)C(F)(F)F)O |
Product Overview
Enpiroline (CAS 52300-95-5), with molecular formula C19H18F6N2O and molecular weight 404.13 g/mol. IUPAC: (R)-piperidin-2-yl-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]-4-pyridinyl]methanol.
Chemical Property Profile of Enpiroline
Property Insights of Enpiroline
The XLogP value of 4.9617 indicates that Enpiroline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.15 Ų, Enpiroline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Enpiroline has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Enpiroline?
The CAS number of Enpiroline is 52300-95-5.
What is the molecular formula of Enpiroline?
The molecular formula of Enpiroline is C19H18F6N2O.
What is the molecular weight of Enpiroline?
The molecular weight of Enpiroline is 404.13 g/mol.
Where can I buy Enpiroline?
You can request a quote for Enpiroline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Enpiroline?
Yes, KEHONG BIO provides custom synthesis services for Enpiroline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.