N-羟基地昔帕明
TL;DR: N-羟基地昔帕明 (CAS 5227-91-8) is a chemical compound with molecular formula C18H22N2O and molecular weight 282.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-羟基地昔帕明
N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-N-methylhydroxylamine
Also Known As: N-Hydroxydesipramine, N-Hydroxydesmethylimipramine, N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-N-methylhydroxylamine, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-hydroxy-N-methyl-, ethyl 2-methyl-5-[(3-nitrophenyl)sulfonylamino]-1-benzofuran-3-carboxylate
| Molecular Formula | C18H22N2O |
|---|---|
| Molecular Weight | 282.17 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 26.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 282.17322 |
| Heavy Atoms | 21 |
| Complexity | 298.0 |
Chemical Identifiers
| CAS Number | 5227-91-8 |
|---|---|
| SMILES | CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)O |
| InChIKey | NLQAJTWNLBARHZ-UHFFFAOYSA-N |
Product Overview
N-羟基地昔帕明 (CAS 5227-91-8), with molecular formula C18H22N2O and molecular weight 282.17 g/mol. IUPAC: N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-N-methylhydroxylamine.
Chemical Property Profile of N-羟基地昔帕明
Property Insights of N-羟基地昔帕明
The XLogP value of 4.3 indicates that N-羟基地昔帕明 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.7 Ų, N-羟基地昔帕明 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-羟基地昔帕明 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-羟基地昔帕明?
The CAS number of N-羟基地昔帕明 is 5227-91-8.
What is the molecular formula of N-羟基地昔帕明?
The molecular formula of N-羟基地昔帕明 is C18H22N2O.
What is the molecular weight of N-羟基地昔帕明?
The molecular weight of N-羟基地昔帕明 is 282.17 g/mol.
Where can I buy N-羟基地昔帕明?
You can request a quote for N-羟基地昔帕明 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-羟基地昔帕明?
Yes, KEHONG BIO provides custom synthesis services for N-羟基地昔帕明 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.