![N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide structure](/static/products/522/522635-47-8.png)
N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide
TL;DR: N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide (CAS 522635-47-8) is a chemical compound with molecular formula C18H14Cl2N2O3S and molecular weight 408.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(6,8-dichloro-4-oxochromen-3-yl)methylideneamino]-5-propan-2-ylthiophene-3-carboxamide
Also Known As: N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide, N-[(1E)-2-(6,8-dichloro-4-oxochromen-3-yl)-1-azavinyl][5-(methylethyl)(3-thien yl)]carboxamide, N-[(6,8-dichloro-4-oxo-chromen-3-yl)methylideneamino]-5-propan-2-yl-thiophene-3-carboxamide, N-[(E)-(6,8-dichloro-4-oxochromen-3-yl)methylideneamino]-5-propan-2-ylthiophene-3-carboxamide
| Molecular Formula | C18H14Cl2N2O3S |
|---|---|
| Molecular Weight | 408.01 g/mol |
| LogP | 5.0486 |
| Topological Polar Surface Area | 71.67 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 408.01022 |
| Heavy Atoms | 26 |
| Complexity | 1069.9738 |
Chemical Identifiers
| CAS Number | 522635-47-8 |
|---|---|
| SMILES | CC(C)C1=CC(=CS1)C(=O)N/N=C/C2=COC3=C(C2=O)C=C(C=C3Cl)Cl |
Product Overview
N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide (CAS 522635-47-8), with molecular formula C18H14Cl2N2O3S and molecular weight 408.01 g/mol. IUPAC: N-[(E)-(6,8-dichloro-4-oxochromen-3-yl)methylideneamino]-5-propan-2-ylthiophene-3-carboxamide.
Chemical Property Profile of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide
Property Insights of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide
The XLogP value of 5.0486 indicates that N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.67 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide. Following Lipinski's Rule of Five, N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide?
The CAS number of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide is 522635-47-8.
What is the molecular formula of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide?
The molecular formula of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide is C18H14Cl2N2O3S.
What is the molecular weight of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide?
The molecular weight of N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide is 408.01 g/mol.
Where can I buy N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide?
You can request a quote for N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-[(E)-(6,8-dichloro-4-oxo-4H-chromen-3-yl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.