![N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/5225/522596-99-2.webp)
N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 522596-99-2) is a chemical compound with molecular formula C22H13BrClF3N6OS and molecular weight 579.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-{4-[(4-bromo-1H-pyrazol-1-yl)methyl]phenyl}-5-(5-chloro-2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-{4-[(4-bromo-1H-pyrazol-1-yl)methyl]phenyl}-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-{4-[(4-bromopyrazolyl)methyl]phenyl}[5-(5-chloro(2-thienyl))-7-(trifluoromet hyl)(8-hydropyrazolo[1,5-a]pyrimidin-2-yl)]carboxamide
| Molecular Formula | C22H13BrClF3N6OS |
|---|---|
| Molecular Weight | 579.97 g/mol |
| LogP | 6.3896 |
| Topological Polar Surface Area | 77.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 579.96954 |
| Heavy Atoms | 35 |
| Complexity | 1543.1096 |
Chemical Identifiers
| CAS Number | 522596-99-2 |
|---|---|
| SMILES | C1=CC(=CC=C1CN2C=C(C=N2)Br)NC(=O)C3=NN4C(=CC(=NC4=C3)C5=CC=C(S5)Cl)C(F)(F)F |
Product Overview
N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 522596-99-2), with molecular formula C22H13BrClF3N6OS and molecular weight 579.97 g/mol. IUPAC: N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 6.3896 indicates that N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.11 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 522596-99-2.
What is the molecular formula of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is C22H13BrClF3N6OS.
What is the molecular weight of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 579.97 g/mol.
Where can I buy N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-[(4-bromopyrazol-1-yl)methyl]phenyl]-5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.