![5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/5225/522596-54-9.webp)
5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 522596-54-9) is a chemical compound with molecular formula C19H16ClF3N6OS and molecular weight 468.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, [5-(5-chloro(2-thienyl))-7-(trifluoromethyl)(8-hydropyrazolo[1,5-a]pyrimidin-2 -yl)]-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]carboxamide, 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
| Molecular Formula | C19H16ClF3N6OS |
|---|---|
| Molecular Weight | 468.07 g/mol |
| LogP | 4.58482 |
| Topological Polar Surface Area | 77.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 468.0747 |
| Heavy Atoms | 31 |
| Complexity | 1275.6378 |
Chemical Identifiers
| CAS Number | 522596-54-9 |
|---|---|
| SMILES | CCN1C=C(C(=N1)C)CNC(=O)C2=NN3C(=CC(=NC3=C2)C4=CC=C(S4)Cl)C(F)(F)F |
Product Overview
5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 522596-54-9), with molecular formula C19H16ClF3N6OS and molecular weight 468.07 g/mol. IUPAC: 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 4.58482 indicates that 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.11 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 522596-54-9.
What is the molecular formula of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is C19H16ClF3N6OS.
What is the molecular weight of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 468.07 g/mol.
Where can I buy 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-(5-chlorothiophen-2-yl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.