4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone structure

4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone

TL;DR: 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone (CAS 52-99-3) is a chemical compound with molecular formula C26H26O7 and molecular weight 450.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-3-(4-phenylmethoxyphenyl)prop-2-en-1-one

Also Known As: 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone, J2.792.367D, (E)-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-3-(4-phenylmethoxyphenyl)prop-2-en-1-one, 3-[4-(benzyloxy)phenyl]-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)prop-2-en-1-one, (2E)-3-[4-(benzyloxy)phenyl]-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)prop-2-en-1-one

CAS: 52-99-3
Molecular Formula C26H26O7
Molecular Weight 450.17 g/mol
LogP 4.9017
Topological Polar Surface Area 83.45 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 10
Exact Mass 450.16785
Heavy Atoms 33
Complexity 1119.8726

Chemical Identifiers

CAS Number 52-99-3
SMILES COC1=C(C(=C(C(=C1C(=O)/C=C/C2=CC=C(C=C2)OCC3=CC=CC=C3)O)OC)OC)OC

Product Overview

4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone (CAS 52-99-3), with molecular formula C26H26O7 and molecular weight 450.17 g/mol. IUPAC: (E)-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-3-(4-phenylmethoxyphenyl)prop-2-en-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone

XLogP
4.9017
TPSA (Topological Polar Surface Area)
83.45
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
10
Heavy Atoms
33
Complexity
1119.8726
Exact Mass
450.16785
Monoisotopic Mass
450.16785
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone

The XLogP value of 4.9017 indicates that 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.45 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone. Following Lipinski's Rule of Five, 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone?

The CAS number of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone is 52-99-3.

What is the molecular formula of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone?

The molecular formula of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone is C26H26O7.

What is the molecular weight of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone?

The molecular weight of 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone is 450.17 g/mol.

Where can I buy 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone?

You can request a quote for 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone?

Yes, KEHONG BIO provides custom synthesis services for 4-Benzyloxy-2'-hydroxy-3',4',5',6'-tetramethoxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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