RefChem:272117 structure

RefChem:272117

TL;DR: RefChem:272117 (CAS 5181-36-2) is a chemical compound with molecular formula C21H22F3NO4 and molecular weight 409.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-O-ethyl 5-O-prop-2-enyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate

Also Known As: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-, ethyl 2-propenyl ester, 3-O-ethyl 5-O-prop-2-enyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate, Ethyl prop-2-en-1-yl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate, Ethyl Prop-2-enyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate, RefChem:272117

CAS: 5181-36-2
Molecular Formula C21H22F3NO4
Molecular Weight 409.15 g/mol
LogP 4.4
Topological Polar Surface Area 64.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 8
Rotatable Bonds 8
Exact Mass 409.1501
Heavy Atoms 29
Complexity 724.0

Chemical Identifiers

CAS Number 5181-36-2
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C(F)(F)F)C(=O)OCC=C)C)C
InChIKey GDVPABWYDPSARA-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (1 patents)

Product Overview

RefChem:272117 (CAS 5181-36-2), with molecular formula C21H22F3NO4 and molecular weight 409.15 g/mol. IUPAC: 3-O-ethyl 5-O-prop-2-enyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:272117

XLogP
4.4
TPSA (Topological Polar Surface Area)
64.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
8
Rotatable Bonds
8
Heavy Atoms
29
Complexity
724.0
Exact Mass
409.1501
Monoisotopic Mass
409.1501
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:272117

The XLogP value of 4.4 indicates that RefChem:272117 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.6 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:272117. Following Lipinski's Rule of Five, RefChem:272117 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:272117?

The CAS number of RefChem:272117 is 5181-36-2.

What is the molecular formula of RefChem:272117?

The molecular formula of RefChem:272117 is C21H22F3NO4.

What is the molecular weight of RefChem:272117?

The molecular weight of RefChem:272117 is 409.15 g/mol.

Where can I buy RefChem:272117?

You can request a quote for RefChem:272117 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:272117?

Yes, KEHONG BIO provides custom synthesis services for RefChem:272117 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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