Corybulbine
TL;DR: Corybulbine (CAS 518-77-4) is a chemical compound with molecular formula C21H25NO4 and molecular weight 355.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(13R,13aS)-2,9,10-trimethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-3-ol
Also Known As: Corybulbine, (13R,13aS)-2,9,10-trimethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-3-ol, (13R,13aS)-2,9,10-Trimethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-3-ol
| Molecular Formula | C21H25NO4 |
|---|---|
| Molecular Weight | 355.18 g/mol |
| LogP | 3.6345 |
| Topological Polar Surface Area | 51.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 355.17834 |
| Heavy Atoms | 26 |
| Complexity | 848.3901 |
Chemical Identifiers
| CAS Number | 518-77-4 |
|---|---|
| SMILES | C[C@H]1[C@H]2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)O)OC |
Product Overview
Corybulbine (CAS 518-77-4), with molecular formula C21H25NO4 and molecular weight 355.18 g/mol. IUPAC: (13R,13aS)-2,9,10-trimethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-3-ol.
Chemical Property Profile of Corybulbine
Property Insights of Corybulbine
The XLogP value of 3.6345 indicates that Corybulbine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.16 Ų, Corybulbine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Corybulbine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Corybulbine?
The CAS number of Corybulbine is 518-77-4.
What is the molecular formula of Corybulbine?
The molecular formula of Corybulbine is C21H25NO4.
What is the molecular weight of Corybulbine?
The molecular weight of Corybulbine is 355.18 g/mol.
Where can I buy Corybulbine?
You can request a quote for Corybulbine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Corybulbine?
Yes, KEHONG BIO provides custom synthesis services for Corybulbine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.