Colchicide
TL;DR: Colchicide (CAS 518-15-0) is a chemical compound with molecular formula C21H23NO5 and molecular weight 369.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Also Known As: Colchicide, Colchicide HCL, 10-Demethoxycolchicine, COLCHICIDE.HCL, Colchicide hydrochloride
| Molecular Formula | C21H23NO5 |
|---|---|
| Molecular Weight | 369.16 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 73.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 369.15762 |
| Heavy Atoms | 27 |
| Complexity | 680.0 |
Chemical Identifiers
| CAS Number | 518-15-0 |
|---|---|
| SMILES | CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=CC(=O)C=C13)OC)OC)OC |
| InChIKey | NXPCQFIROMOQEV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Colchicide (CAS 518-15-0), with molecular formula C21H23NO5 and molecular weight 369.16 g/mol. IUPAC: N-(1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide.
Chemical Property Profile of Colchicide
Property Insights of Colchicide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicide. The TPSA of 73.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicide. Following Lipinski's Rule of Five, Colchicide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicide?
The CAS number of Colchicide is 518-15-0.
What is the molecular formula of Colchicide?
The molecular formula of Colchicide is C21H23NO5.
What is the molecular weight of Colchicide?
The molecular weight of Colchicide is 369.16 g/mol.
Where can I buy Colchicide?
You can request a quote for Colchicide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicide?
Yes, KEHONG BIO provides custom synthesis services for Colchicide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.