(+)-Mefloquine
TL;DR: (+)-Mefloquine (CAS 51744-83-3) is a chemical compound with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol
Also Known As: mefloquine, (+)-Mefloquine, Lariam, Mefloquina, Mefloquinum
| Molecular Formula | C17H16F6N2O |
|---|---|
| Molecular Weight | 378.12 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 45.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.11667 |
| Heavy Atoms | 26 |
| Complexity | 483.0 |
Chemical Identifiers
| CAS Number | 51744-83-3 |
|---|---|
| SMILES | C1CCN[C@@H](C1)[C@@H](C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O |
| InChIKey | XEEQGYMUWCZPDN-SWLSCSKDSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+)-Mefloquine (CAS 51744-83-3), with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol. IUPAC: (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol.
Chemical Property Profile of (+)-Mefloquine
Property Insights of (+)-Mefloquine
The XLogP value of 3.6 indicates that (+)-Mefloquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, (+)-Mefloquine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+)-Mefloquine has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Mefloquine?
The CAS number of (+)-Mefloquine is 51744-83-3.
What is the molecular formula of (+)-Mefloquine?
The molecular formula of (+)-Mefloquine is C17H16F6N2O.
What is the molecular weight of (+)-Mefloquine?
The molecular weight of (+)-Mefloquine is 378.12 g/mol.
Where can I buy (+)-Mefloquine?
You can request a quote for (+)-Mefloquine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Mefloquine?
Yes, KEHONG BIO provides custom synthesis services for (+)-Mefloquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.