2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
TL;DR: 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide (CAS 516480-79-8) is a chemical compound with molecular formula C20H14ClN3O2 and molecular weight 363.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide
Also Known As: Chk2 Inhibitor II, CHK2iII compound, 2-arylbenzimidazole, CHK2in, 4a9r
| Molecular Formula | C20H14ClN3O2 |
|---|---|
| Molecular Weight | 363.08 g/mol |
| LogP | 4.7745 |
| Topological Polar Surface Area | 81.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 363.07745 |
| Heavy Atoms | 26 |
| Complexity | 1086.4575 |
Chemical Identifiers
| CAS Number | 516480-79-8 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl |
Product Overview
2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide (CAS 516480-79-8), with molecular formula C20H14ClN3O2 and molecular weight 363.08 g/mol. IUPAC: 2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide.
Chemical Property Profile of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
Property Insights of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
The XLogP value of 4.7745 indicates that 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide. Following Lipinski's Rule of Five, 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide?
The CAS number of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide is 516480-79-8.
What is the molecular formula of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide?
The molecular formula of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide is C20H14ClN3O2.
What is the molecular weight of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide?
The molecular weight of 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide is 363.08 g/mol.
Where can I buy 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide?
You can request a quote for 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.