4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide
TL;DR: 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide (CAS 516459-78-2) is a chemical compound with molecular formula C18H20N2O2S and molecular weight 328.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide
Also Known As: 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide, VU0047446-1, 1-{[(4-phenoxyphenyl)amino]thioxomethyl}piperidin-4-ol, 4-hydroxy-N-(4-phenoxyphenyl)-1-piperidinecarbothioamide, 4-HYDROXY-N-(4-PHENOXYPHENYL)TETRAHYDRO-1(2H)-PYRIDINECARBOTHIOAMIDE
| Molecular Formula | C18H20N2O2S |
|---|---|
| Molecular Weight | 328.12 g/mol |
| LogP | 3.6324 |
| Topological Polar Surface Area | 44.73 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 328.12454 |
| Heavy Atoms | 23 |
| Complexity | 637.831 |
Chemical Identifiers
| CAS Number | 516459-78-2 |
|---|---|
| SMILES | C1CN(CCC1O)C(=S)NC2=CC=C(C=C2)OC3=CC=CC=C3 |
Product Overview
4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide (CAS 516459-78-2), with molecular formula C18H20N2O2S and molecular weight 328.12 g/mol. IUPAC: 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide.
Chemical Property Profile of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide
Property Insights of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide
The XLogP value of 3.6324 indicates that 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.73 Ų, 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide?
The CAS number of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide is 516459-78-2.
What is the molecular formula of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide?
The molecular formula of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide is C18H20N2O2S.
What is the molecular weight of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide?
The molecular weight of 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide is 328.12 g/mol.
Where can I buy 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide?
You can request a quote for 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide?
Yes, KEHONG BIO provides custom synthesis services for 4-hydroxy-N-(4-phenoxyphenyl)piperidine-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.