Cortol
TL;DR: Cortol (CAS 516-38-1) is a chemical compound with molecular formula C21H36O5 and molecular weight 368.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,5R,8S,9S,10S,11S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,11,17-triol
Also Known As: Cortol, alpha-cortol, 20alpha-Cortol, a-cortol, .alpha.-Cortol
| Molecular Formula | C21H36O5 |
|---|---|
| Molecular Weight | 368.26 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 368.2563 |
| Heavy Atoms | 26 |
| Complexity | 555.0 |
Chemical Identifiers
| CAS Number | 516-38-1 |
|---|---|
| SMILES | C[C@]12CC[C@H](C[C@H]1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4([C@H](CO)O)O)C)O)O |
| InChIKey | FFPUNPBUZDTHJI-XPOJVAQCSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Cortol (CAS 516-38-1), with molecular formula C21H36O5 and molecular weight 368.26 g/mol. IUPAC: (3R,5R,8S,9S,10S,11S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,11,17-triol.
Chemical Property Profile of Cortol
Property Insights of Cortol
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Cortol. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Cortol. Following Lipinski's Rule of Five, Cortol has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cortol?
The CAS number of Cortol is 516-38-1.
What is the molecular formula of Cortol?
The molecular formula of Cortol is C21H36O5.
What is the molecular weight of Cortol?
The molecular weight of Cortol is 368.26 g/mol.
Where can I buy Cortol?
You can request a quote for Cortol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cortol?
Yes, KEHONG BIO provides custom synthesis services for Cortol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.