Negletein structure

Negletein

TL;DR: Negletein (CAS 51576-10-4) is a chemical compound with molecular formula C16H12O5 and molecular weight 284.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5,6-dihydroxy-7-methoxy-2-phenylchromen-4-one

Also Known As: Negletein, 5,6-Dihydroxy-7-methoxyflavone, 7-O-Methylbaicalein, Baicalein-7-methylether, neglectein

CAS: 51576-10-4
Molecular Formula C16H12O5
Molecular Weight 284.07 g/mol
LogP 3.0
Topological Polar Surface Area 76.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 284.06848
Heavy Atoms 21
Complexity 426.0

Chemical Identifiers

CAS Number 51576-10-4
SMILES COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)O
InChIKey ZTHLHHDJRXJGRX-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Biotechnology (2 patents) Heterocyclic Building Blocks (10 patents) Pharmaceutical Intermediates (36 patents) Plastic Additives (2 patents) Polymer Intermediates (1 patents)

Product Overview

Negletein (CAS 51576-10-4), with molecular formula C16H12O5 and molecular weight 284.07 g/mol. IUPAC: 5,6-dihydroxy-7-methoxy-2-phenylchromen-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Negletein

XLogP
3.0
TPSA (Topological Polar Surface Area)
76.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
21
Complexity
426.0
Exact Mass
284.06848
Monoisotopic Mass
284.06848
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Negletein

The XLogP value of 3.0 indicates that Negletein is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Negletein. Following Lipinski's Rule of Five, Negletein has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Negletein?

The CAS number of Negletein is 51576-10-4.

What is the molecular formula of Negletein?

The molecular formula of Negletein is C16H12O5.

What is the molecular weight of Negletein?

The molecular weight of Negletein is 284.07 g/mol.

Where can I buy Negletein?

You can request a quote for Negletein directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Negletein?

Yes, KEHONG BIO provides custom synthesis services for Negletein and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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