Naloxone Hydrochloride
TL;DR: Naloxone Hydrochloride (CAS 51481-60-8) is a chemical compound with molecular formula C19H22ClNO4 and molecular weight 363.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
Also Known As: Naloxone hydrochloride, Naloxone HCl, Narcan, Narcanti, Evzio
| Molecular Formula | C19H22ClNO4 |
|---|---|
| Molecular Weight | 363.12 g/mol |
| LogP | 1.7232 |
| Topological Polar Surface Area | 70.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 363.12375 |
| Heavy Atoms | 25 |
| Complexity | 780.93274 |
Chemical Identifiers
| CAS Number | 51481-60-8 |
|---|---|
| SMILES | C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl |
Product Overview
Naloxone Hydrochloride (CAS 51481-60-8), with molecular formula C19H22ClNO4 and molecular weight 363.12 g/mol. IUPAC: (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride.
Chemical Property Profile of Naloxone Hydrochloride
Property Insights of Naloxone Hydrochloride
The XLogP value of 1.7232 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naloxone Hydrochloride. The TPSA of 70.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Naloxone Hydrochloride. Following Lipinski's Rule of Five, Naloxone Hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naloxone Hydrochloride?
The CAS number of Naloxone Hydrochloride is 51481-60-8.
What is the molecular formula of Naloxone Hydrochloride?
The molecular formula of Naloxone Hydrochloride is C19H22ClNO4.
What is the molecular weight of Naloxone Hydrochloride?
The molecular weight of Naloxone Hydrochloride is 363.12 g/mol.
Where can I buy Naloxone Hydrochloride?
You can request a quote for Naloxone Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naloxone Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Naloxone Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.