5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
TL;DR: 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 5148-91-4) is a chemical compound with molecular formula C18H13ClFNO3 and molecular weight 345.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
Also Known As: 5-chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid, 5-chloro-2-(5-fluoro-2-methoxyphenyl)-8-methyl-4-quinolinecarboxylic acid, 5-chloro-2-(5-fluoro-2-methoxy-phenyl)-8-methyl-quinoline-4-carboxylic Acid
| Molecular Formula | C18H13ClFNO3 |
|---|---|
| Molecular Weight | 345.06 g/mol |
| LogP | 4.70952 |
| Topological Polar Surface Area | 59.42 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 345.0568 |
| Heavy Atoms | 24 |
| Complexity | 972.12537 |
Chemical Identifiers
| CAS Number | 5148-91-4 |
|---|---|
| SMILES | CC1=C2C(=C(C=C1)Cl)C(=CC(=N2)C3=C(C=CC(=C3)F)OC)C(=O)O |
Product Overview
5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 5148-91-4), with molecular formula C18H13ClFNO3 and molecular weight 345.06 g/mol. IUPAC: 5-chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid.
Chemical Property Profile of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
Property Insights of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
The XLogP value of 4.70952 indicates that 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.42 Ų, 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid?
The CAS number of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid is 5148-91-4.
What is the molecular formula of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid?
The molecular formula of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid is C18H13ClFNO3.
What is the molecular weight of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid?
The molecular weight of 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid is 345.06 g/mol.
Where can I buy 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid?
You can request a quote for 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 5-Chloro-2-(5-fluoro-2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.