![N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/514/514220-37-2.png)
N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 514220-37-2) is a chemical compound with molecular formula C21H9F8N5O and molecular weight 499.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N'-[(E)-(pentafluorophenyl)methylidene]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-(2,3,4,5,6-pentafluorobenzylidene)-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'~2~-[(E)-1-(2,3,4,5,6-PENTAFLUOROPHENYL)METHYLIDENE]-5-PHENYL-7-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOHYDRAZIDE
| Molecular Formula | C21H9F8N5O |
|---|---|
| Molecular Weight | 499.07 g/mol |
| LogP | 4.8745 |
| Topological Polar Surface Area | 71.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 499.06793 |
| Heavy Atoms | 35 |
| Complexity | 1452.0845 |
Chemical Identifiers
| CAS Number | 514220-37-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)N/N=C/C4=C(C(=C(C(=C4F)F)F)F)F |
Product Overview
N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 514220-37-2), with molecular formula C21H9F8N5O and molecular weight 499.07 g/mol. IUPAC: N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 4.8745 indicates that N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.65 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 514220-37-2.
What is the molecular formula of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is C21H9F8N5O.
What is the molecular weight of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 499.07 g/mol.
Where can I buy N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[(E)-(2,3,4,5,6-pentafluorophenyl)methylideneamino]-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.