![1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine structure](/static/products/5127/512775-99-4.webp)
1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine
TL;DR: 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine (CAS 512775-99-4) is a chemical compound with molecular formula C18H18ClF3N2 and molecular weight 354.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-chlorophenyl)-[2-(trifluoromethyl)phenyl]methyl]piperazine
Also Known As: 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine, 1-{(4-chlorophenyl)[2-(trifluoromethyl)phenyl]methyl}piperazine, 1-[(4-chlorophenyl)-[2-(trifluoromethyl)phenyl]methyl]piperazine
| Molecular Formula | C18H18ClF3N2 |
|---|---|
| Molecular Weight | 354.11 g/mol |
| LogP | 4.3534 |
| Topological Polar Surface Area | 15.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 354.11105 |
| Heavy Atoms | 24 |
| Complexity | 679.4084 |
Chemical Identifiers
| CAS Number | 512775-99-4 |
|---|---|
| SMILES | C1CN(CCN1)C(C2=CC=C(C=C2)Cl)C3=CC=CC=C3C(F)(F)F |
Product Overview
1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine (CAS 512775-99-4), with molecular formula C18H18ClF3N2 and molecular weight 354.11 g/mol. IUPAC: 1-[(4-chlorophenyl)-[2-(trifluoromethyl)phenyl]methyl]piperazine.
Chemical Property Profile of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine
Property Insights of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine
The XLogP value of 4.3534 indicates that 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.27 Ų, 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine?
The CAS number of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine is 512775-99-4.
What is the molecular formula of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine?
The molecular formula of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine is C18H18ClF3N2.
What is the molecular weight of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine?
The molecular weight of 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine is 354.11 g/mol.
Where can I buy 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine?
You can request a quote for 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-((4-Chlorophenyl)[2-(trifluoromethyl)phenyl]methyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.