N-(2-Hydroxyethyl)lorazepam
TL;DR: N-(2-Hydroxyethyl)lorazepam (CAS 51230-35-4) is a chemical compound with molecular formula C17H14Cl2N2O3 and molecular weight 364.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-3H-1,4-benzodiazepin-2-one
Also Known As: N-(2-Hydroxyethyl)lorazepam, SAS 632, 5-25-02-00252 (Beilstein Handbook Reference), 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-3H-1,4-benzodiazepin-2-one, 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-chlorophenyl)-(2- hydroxyethyl)-
| Molecular Formula | C17H14Cl2N2O3 |
|---|---|
| Molecular Weight | 364.04 g/mol |
| LogP | 2.4881 |
| Topological Polar Surface Area | 73.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 364.03815 |
| Heavy Atoms | 24 |
| Complexity | 823.233 |
Chemical Identifiers
| CAS Number | 51230-35-4 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCO)O)Cl |
Product Overview
N-(2-Hydroxyethyl)lorazepam (CAS 51230-35-4), with molecular formula C17H14Cl2N2O3 and molecular weight 364.04 g/mol. IUPAC: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of N-(2-Hydroxyethyl)lorazepam
Property Insights of N-(2-Hydroxyethyl)lorazepam
The XLogP value of 2.4881 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(2-Hydroxyethyl)lorazepam. The TPSA of 73.13 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2-Hydroxyethyl)lorazepam. Following Lipinski's Rule of Five, N-(2-Hydroxyethyl)lorazepam has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-Hydroxyethyl)lorazepam?
The CAS number of N-(2-Hydroxyethyl)lorazepam is 51230-35-4.
What is the molecular formula of N-(2-Hydroxyethyl)lorazepam?
The molecular formula of N-(2-Hydroxyethyl)lorazepam is C17H14Cl2N2O3.
What is the molecular weight of N-(2-Hydroxyethyl)lorazepam?
The molecular weight of N-(2-Hydroxyethyl)lorazepam is 364.04 g/mol.
Where can I buy N-(2-Hydroxyethyl)lorazepam?
You can request a quote for N-(2-Hydroxyethyl)lorazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-Hydroxyethyl)lorazepam?
Yes, KEHONG BIO provides custom synthesis services for N-(2-Hydroxyethyl)lorazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.