Ro 6-5403 structure

Ro 6-5403

TL;DR: Ro 6-5403 (CAS 51018-08-7) is a chemical compound with molecular formula C23H26O2 and molecular weight 334.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,9S,13S,14S)-17-ethynyl-17-hydroxy-13-methyl-10-[(E)-prop-1-enyl]-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one

Also Known As: Ro 6-5403, 19 beta-cis-Ethylidene-17alpha-ethynyl-17beta-hydroxy-1,4,6-androstatrien-3-one, (8R,9S,13S,14S)-17-ethynyl-17-hydroxy-13-methyl-10-[(E)-prop-1-enyl]-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one, 17-hydroxy-10-(1-propenyl)-(17 alpha)-19-norpregna-1,4,6-trien-20-yn-3-one, 17-Hydroxy-10-(1-propenyl)-(17alpha)-19-norpregna-1,4,6-trien-20-yn-3-one

CAS: 51018-08-7
Molecular Formula C23H26O2
Molecular Weight 334.19 g/mol
LogP 3.9908
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 334.19327
Heavy Atoms 25
Complexity 776.4047

Chemical Identifiers

CAS Number 51018-08-7
SMILES C/C=C/C12C=CC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4(C#C)O)C

Product Overview

Ro 6-5403 (CAS 51018-08-7), with molecular formula C23H26O2 and molecular weight 334.19 g/mol. IUPAC: (8R,9S,13S,14S)-17-ethynyl-17-hydroxy-13-methyl-10-[(E)-prop-1-enyl]-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ro 6-5403

XLogP
3.9908
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
25
Complexity
776.4047
Exact Mass
334.19327
Monoisotopic Mass
334.19327
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ro 6-5403

The XLogP value of 3.9908 indicates that Ro 6-5403 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, Ro 6-5403 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ro 6-5403 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ro 6-5403?

The CAS number of Ro 6-5403 is 51018-08-7.

What is the molecular formula of Ro 6-5403?

The molecular formula of Ro 6-5403 is C23H26O2.

What is the molecular weight of Ro 6-5403?

The molecular weight of Ro 6-5403 is 334.19 g/mol.

Where can I buy Ro 6-5403?

You can request a quote for Ro 6-5403 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ro 6-5403?

Yes, KEHONG BIO provides custom synthesis services for Ro 6-5403 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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