![8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one structure](/static/products/5089/50892-62-1.webp)
8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
TL;DR: 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one (CAS 50892-62-1) is a chemical compound with molecular formula C13H9ClN2O and molecular weight 244.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-chloro-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
Also Known As: 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one, Clozapine EP Impurity A, Clozapine Impurity A, 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one, Chk1_8
| Molecular Formula | C13H9ClN2O |
|---|---|
| Molecular Weight | 244.04 g/mol |
| LogP | 3.6493 |
| Topological Polar Surface Area | 41.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 244.04034 |
| Heavy Atoms | 17 |
| Complexity | 610.11847 |
Chemical Identifiers
| CAS Number | 50892-62-1 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=O)NC3=C(N2)C=CC(=C3)Cl |
Product Overview
8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one (CAS 50892-62-1), with molecular formula C13H9ClN2O and molecular weight 244.04 g/mol. IUPAC: 3-chloro-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one.
Chemical Property Profile of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Property Insights of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
The XLogP value of 3.6493 indicates that 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.13 Ų, 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one?
The CAS number of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is 50892-62-1.
What is the molecular formula of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one?
The molecular formula of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is C13H9ClN2O.
What is the molecular weight of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one?
The molecular weight of 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is 244.04 g/mol.
Where can I buy 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one?
You can request a quote for 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one?
Yes, KEHONG BIO provides custom synthesis services for 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.