RefChem:284354
TL;DR: RefChem:284354 (CAS 50871-44-8) is a chemical compound with molecular formula C18H26ClN3O2S and molecular weight 383.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-(4-propan-2-ylphenyl)-1,3-thiazol-4-one;hydrochloride
Also Known As: LA 1461, N-Hydroxyethylpiperazino-2 p-isopropylphenyl-5 thiazolinone HCl, N-Hydroxyethylpiperazino-2 p-isopropylphenyl-5 thiazolinone HCl [French], 4(5H)-Thiazolone, 2-(4-(2-hydroxyethyl)-1-piperazinyl)-5-(4-(1-methylethyl)phenyl)-, monohydrochloride, 2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-(4-propan-2-ylphenyl)-1,3-thiazol-4-one hydrochloride
| Molecular Formula | C18H26ClN3O2S |
|---|---|
| Molecular Weight | 383.14 g/mol |
| LogP | 2.5122 |
| Topological Polar Surface Area | 56.14 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 383.14343 |
| Heavy Atoms | 25 |
| Complexity | 613.25214 |
Chemical Identifiers
| CAS Number | 50871-44-8 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2C(=O)N=C(S2)N3CCN(CC3)CCO.Cl |
Product Overview
RefChem:284354 (CAS 50871-44-8), with molecular formula C18H26ClN3O2S and molecular weight 383.14 g/mol. IUPAC: 2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-(4-propan-2-ylphenyl)-1,3-thiazol-4-one;hydrochloride.
Chemical Property Profile of RefChem:284354
Property Insights of RefChem:284354
The XLogP value of 2.5122 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RefChem:284354. With a topological polar surface area (TPSA) of 56.14 Ų, RefChem:284354 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:284354 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:284354?
The CAS number of RefChem:284354 is 50871-44-8.
What is the molecular formula of RefChem:284354?
The molecular formula of RefChem:284354 is C18H26ClN3O2S.
What is the molecular weight of RefChem:284354?
The molecular weight of RefChem:284354 is 383.14 g/mol.
Where can I buy RefChem:284354?
You can request a quote for RefChem:284354 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:284354?
Yes, KEHONG BIO provides custom synthesis services for RefChem:284354 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.