Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate structure

Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate

TL;DR: Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate (CAS 50469-23-3) is a chemical compound with molecular formula C25H28N2O6 and molecular weight 452.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

diethyl 2-acetamido-2-[(5-phenylmethoxy-1H-indol-3-yl)methyl]propanedioate

Also Known As: Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate, diethyl acetamido{[5-(benzyloxy)-1h-indol-3-yl]methyl}malonate, diethyl 2-acetamido-2-[(5-phenylmethoxy-1H-indol-3-yl)methyl, diethyl 2-acetamido-2-[(5-phenylmethoxy-1H-indol-3-yl)methyl]propanedioate, Diethyl acetamido{[5-(benzyloxy)-1H-indol-3-yl]methyl}propanedioate

CAS: 50469-23-3
Molecular Formula C25H28N2O6
Molecular Weight 452.19 g/mol
LogP 3.7
Topological Polar Surface Area 107.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 12
Exact Mass 452.19473
Heavy Atoms 33
Complexity 660.0

Chemical Identifiers

CAS Number 50469-23-3
SMILES CCOC(=O)C(CC1=CNC2=C1C=C(C=C2)OCC3=CC=CC=C3)(C(=O)OCC)NC(=O)C
InChIKey AIHVUEYJDRTUHZ-UHFFFAOYSA-N

Product Overview

Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate (CAS 50469-23-3), with molecular formula C25H28N2O6 and molecular weight 452.19 g/mol. IUPAC: diethyl 2-acetamido-2-[(5-phenylmethoxy-1H-indol-3-yl)methyl]propanedioate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate

XLogP
3.7
TPSA (Topological Polar Surface Area)
107.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
12
Heavy Atoms
33
Complexity
660.0
Exact Mass
452.19473
Monoisotopic Mass
452.19473
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate

The XLogP value of 3.7 indicates that Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate. Following Lipinski's Rule of Five, Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate?

The CAS number of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate is 50469-23-3.

What is the molecular formula of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate?

The molecular formula of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate is C25H28N2O6.

What is the molecular weight of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate?

The molecular weight of Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate is 452.19 g/mol.

Where can I buy Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate?

You can request a quote for Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate?

Yes, KEHONG BIO provides custom synthesis services for Diethyl 2-acetamido-2-((5-(phenylmethoxy)indol-3-yl)methyl)malonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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