![4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide structure](/static/products/5019/501924-62-5.webp)
4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
TL;DR: 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide (CAS 501924-62-5) is a chemical compound with molecular formula C18H18F3N3S and molecular weight 365.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
Also Known As: 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide, 4-phenyl-N-(2-(trifluoromethyl)phenyl)piperazine-1-carbothioamide, F1651-0032, (4-phenylpiperazinyl){[2-(trifluoromethyl)phenyl]amino}methane-1-thione
| Molecular Formula | C18H18F3N3S |
|---|---|
| Molecular Weight | 365.12 g/mol |
| LogP | 4.2244 |
| Topological Polar Surface Area | 18.51 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 365.11734 |
| Heavy Atoms | 25 |
| Complexity | 725.8462 |
Chemical Identifiers
| CAS Number | 501924-62-5 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=S)NC3=CC=CC=C3C(F)(F)F |
Product Overview
4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide (CAS 501924-62-5), with molecular formula C18H18F3N3S and molecular weight 365.12 g/mol. IUPAC: 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide.
Chemical Property Profile of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
Property Insights of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
The XLogP value of 4.2244 indicates that 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.51 Ų, 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide?
The CAS number of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide is 501924-62-5.
What is the molecular formula of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide?
The molecular formula of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide is C18H18F3N3S.
What is the molecular weight of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide?
The molecular weight of 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide is 365.12 g/mol.
Where can I buy 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide?
You can request a quote for 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide?
Yes, KEHONG BIO provides custom synthesis services for 4-phenyl-N-[2-(trifluoromethyl)phenyl]piperazine-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.