![(5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione structure](/static/products/501/501350-52-3.png)
(5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione
TL;DR: (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione (CAS 501350-52-3) is a chemical compound with molecular formula C20H20ClN3O3S and molecular weight 417.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione
Also Known As: (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione, (5E)-5-{[5-(3-chlorophenyl)furan-2-yl]methylidene}-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione, (E)-5-((5-(3-chlorophenyl)furan-2-yl)methylene)-3-((4-methylpiperazin-1-yl)methyl)thiazolidine-2,4-dione, 5-{[5-(3-chlorophenyl)(2-furyl)]methylene}-3-[(4-methylpiperazinyl)methyl]-1,3 -thiazolidine-2,4-dione
| Molecular Formula | C20H20ClN3O3S |
|---|---|
| Molecular Weight | 417.09 g/mol |
| LogP | 3.8412 |
| Topological Polar Surface Area | 57.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 417.0914 |
| Heavy Atoms | 28 |
| Complexity | 934.28204 |
Chemical Identifiers
| CAS Number | 501350-52-3 |
|---|---|
| SMILES | CN1CCN(CC1)CN2C(=O)/C(=C\C3=CC=C(O3)C4=CC(=CC=C4)Cl)/SC2=O |
Product Overview
(5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione (CAS 501350-52-3), with molecular formula C20H20ClN3O3S and molecular weight 417.09 g/mol. IUPAC: (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione
Property Insights of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione
The XLogP value of 3.8412 indicates that (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.0 Ų, (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione?
The CAS number of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione is 501350-52-3.
What is the molecular formula of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione?
The molecular formula of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione is C20H20ClN3O3S.
What is the molecular weight of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione?
The molecular weight of (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione is 417.09 g/mol.
Where can I buy (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione?
You can request a quote for (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-3-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazolidine-2,4-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.