![2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline structure](/static/products/5008/5008-25-3.webp)
2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline
TL;DR: 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline (CAS 5008-25-3) is a chemical compound with molecular formula C21H20F3N3 and molecular weight 371.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline
Also Known As: 2-[piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline, 2-{(Piperazin-1-yl)[4-(trifluoromethyl)phenyl]methyl}quinoline
| Molecular Formula | C21H20F3N3 |
|---|---|
| Molecular Weight | 371.16 g/mol |
| LogP | 4.2482 |
| Topological Polar Surface Area | 28.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 371.16092 |
| Heavy Atoms | 27 |
| Complexity | 915.8532 |
Chemical Identifiers
| CAS Number | 5008-25-3 |
|---|---|
| SMILES | C1CN(CCN1)C(C2=CC=C(C=C2)C(F)(F)F)C3=NC4=CC=CC=C4C=C3 |
Product Overview
2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline (CAS 5008-25-3), with molecular formula C21H20F3N3 and molecular weight 371.16 g/mol. IUPAC: 2-[piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline.
Chemical Property Profile of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline
Property Insights of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline
The XLogP value of 4.2482 indicates that 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.16 Ų, 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline?
The CAS number of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline is 5008-25-3.
What is the molecular formula of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline?
The molecular formula of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline is C21H20F3N3.
What is the molecular weight of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline?
The molecular weight of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline is 371.16 g/mol.
Where can I buy 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline?
You can request a quote for 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline?
Yes, KEHONG BIO provides custom synthesis services for 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.