MK 0873
TL;DR: MK 0873 (CAS 500355-52-2) is a chemical compound with molecular formula C25H18N4O3 and molecular weight 422.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide
Also Known As: MK 0873, MK-0873 (dermatological, psoriasis), compound 20 [PMID: 18835163], N-Cyclopropyl-1-(3-((1-oxidopyridin-3-yl)ethynyl)phenyl)-1,4-dihydro(1,8)naphthyridin-4-one-3-carboxamide, 1,8-Naphthyridine-3-carboxamide, N-cyclopropyl-1,4-dihydro-1-(3-((1-oxido-3-pyridinyl)ethynyl)phenyl)-4-oxo-
| Molecular Formula | C25H18N4O3 |
|---|---|
| Molecular Weight | 422.14 g/mol |
| LogP | 2.3111 |
| Topological Polar Surface Area | 90.93 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 422.13788 |
| Heavy Atoms | 32 |
| Complexity | 1476.0354 |
Chemical Identifiers
| CAS Number | 500355-52-2 |
|---|---|
| SMILES | C1CC1NC(=O)C2=CN(C3=C(C2=O)C=CC=N3)C4=CC=CC(=C4)C#CC5=C[N+](=CC=C5)[O-] |
Product Overview
MK 0873 (CAS 500355-52-2), with molecular formula C25H18N4O3 and molecular weight 422.14 g/mol. IUPAC: N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide.
Chemical Property Profile of MK 0873
Property Insights of MK 0873
The XLogP value of 2.3111 suggests moderate lipophilicity, balancing water solubility and membrane permeability for MK 0873. The TPSA of 90.93 Ų falls within the moderate polarity range, balancing permeability and solubility for MK 0873. Following Lipinski's Rule of Five, MK 0873 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of MK 0873?
The CAS number of MK 0873 is 500355-52-2.
What is the molecular formula of MK 0873?
The molecular formula of MK 0873 is C25H18N4O3.
What is the molecular weight of MK 0873?
The molecular weight of MK 0873 is 422.14 g/mol.
Where can I buy MK 0873?
You can request a quote for MK 0873 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for MK 0873?
Yes, KEHONG BIO provides custom synthesis services for MK 0873 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.