F1443-3878
TL;DR: F1443-3878 (CAS 500201-72-9) is a chemical compound with molecular formula C20H20FN3O4S2 and molecular weight 449.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-fluorophenyl)-N-[(4-morpholin-4-ylsulfonylphenyl)carbamothioyl]prop-2-enamide
Also Known As: F1443-3878, (2E)-3-(4-fluorophenyl)-N-{[4-(morpholin-4-ylsulfonyl)phenyl]carbamothioyl}prop-2-enamide, 1-[(2E)-3-(4-fluorophenyl)prop-2-enoyl]-3-[4-(morpholine-4-sulfonyl)phenyl]thiourea, (E)-3-(4-fluorophenyl)-N-[(4-morpholin-4-ylsulfonylphenyl)carbamothioyl]prop-2-enamide, (E)-3-(4-fluorophenyl)-N-((4-(morpholinosulfonyl)phenyl)carbamothioyl)acrylamide
| Molecular Formula | C20H20FN3O4S2 |
|---|---|
| Molecular Weight | 449.09 g/mol |
| LogP | 2.373 |
| Topological Polar Surface Area | 87.74 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 449.08792 |
| Heavy Atoms | 30 |
| Complexity | 1032.7262 |
Chemical Identifiers
| CAS Number | 500201-72-9 |
|---|---|
| SMILES | C1COCCN1S(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)/C=C/C3=CC=C(C=C3)F |
Product Overview
F1443-3878 (CAS 500201-72-9), with molecular formula C20H20FN3O4S2 and molecular weight 449.09 g/mol. IUPAC: (E)-3-(4-fluorophenyl)-N-[(4-morpholin-4-ylsulfonylphenyl)carbamothioyl]prop-2-enamide.
Chemical Property Profile of F1443-3878
Property Insights of F1443-3878
The XLogP value of 2.373 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F1443-3878. The TPSA of 87.74 Ų falls within the moderate polarity range, balancing permeability and solubility for F1443-3878. Following Lipinski's Rule of Five, F1443-3878 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1443-3878?
The CAS number of F1443-3878 is 500201-72-9.
What is the molecular formula of F1443-3878?
The molecular formula of F1443-3878 is C20H20FN3O4S2.
What is the molecular weight of F1443-3878?
The molecular weight of F1443-3878 is 449.09 g/mol.
Where can I buy F1443-3878?
You can request a quote for F1443-3878 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1443-3878?
Yes, KEHONG BIO provides custom synthesis services for F1443-3878 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.