![2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole structure](/static/products/4997/499785-53-4.webp)
2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole
TL;DR: 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole (CAS 499785-53-4) is a chemical compound with molecular formula C11H7ClF3NS and molecular weight 276.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole
Also Known As: 2-(chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole, 2-(CHLOROMETHYL)-4-(4-(TRIFLUOROMETHYL)PHENYL)-1,3-THIAZOLE, 2-BROMO-4-METHOXY-5-(BENZYLOXY)BENZOIC ACID, 2-(Chloromethyl)-4-(4-(trifluoromethyl)phenyl)thiazole, 2-(3-Hydroxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
| Molecular Formula | C11H7ClF3NS |
|---|---|
| Molecular Weight | 276.99 g/mol |
| LogP | 4.5677 |
| Topological Polar Surface Area | 12.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 276.994 |
| Heavy Atoms | 17 |
| Complexity | 504.18024 |
Chemical Identifiers
| CAS Number | 499785-53-4 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CSC(=N2)CCl)C(F)(F)F |
Product Overview
2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole (CAS 499785-53-4), with molecular formula C11H7ClF3NS and molecular weight 276.99 g/mol. IUPAC: 2-(chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole.
Chemical Property Profile of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole
Property Insights of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole
The XLogP value of 4.5677 indicates that 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.89 Ų, 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole?
The CAS number of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole is 499785-53-4.
What is the molecular formula of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole?
The molecular formula of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole is C11H7ClF3NS.
What is the molecular weight of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole?
The molecular weight of 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole is 276.99 g/mol.
Where can I buy 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole?
You can request a quote for 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 2-(Chloromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.