4-Fluoropyrrolidine-2-carboxylic acid
TL;DR: 4-Fluoropyrrolidine-2-carboxylic acid (CAS 499769-96-9) is a chemical compound with molecular formula C5H8FNO2 and molecular weight 133.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-fluoropyrrolidine-2-carboxylic acid
Also Known As: 4-Fluoroproline, 4-fluoropyrrolidine-2-carboxylic acid, cis-4-Fluoro-L-proline, trans-4-Fluoro-l-proline, (Boc-Cys-OH)2
| Molecular Formula | C5H8FNO2 |
|---|---|
| Molecular Weight | 133.05 g/mol |
| LogP | -2.3 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 133.05391 |
| Heavy Atoms | 9 |
| Complexity | 128.0 |
Chemical Identifiers
| CAS Number | 499769-96-9 |
|---|---|
| SMILES | C1C(CNC1C(=O)O)F |
| InChIKey | ZIWHMENIDGOELV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-Fluoropyrrolidine-2-carboxylic acid (CAS 499769-96-9), with molecular formula C5H8FNO2 and molecular weight 133.05 g/mol. IUPAC: 4-fluoropyrrolidine-2-carboxylic acid.
Chemical Property Profile of 4-Fluoropyrrolidine-2-carboxylic acid
Property Insights of 4-Fluoropyrrolidine-2-carboxylic acid
The XLogP value of -2.3 indicates that 4-Fluoropyrrolidine-2-carboxylic acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 49.3 Ų, 4-Fluoropyrrolidine-2-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoropyrrolidine-2-carboxylic acid has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Fluoropyrrolidine-2-carboxylic acid?
The CAS number of 4-Fluoropyrrolidine-2-carboxylic acid is 499769-96-9.
What is the molecular formula of 4-Fluoropyrrolidine-2-carboxylic acid?
The molecular formula of 4-Fluoropyrrolidine-2-carboxylic acid is C5H8FNO2.
What is the molecular weight of 4-Fluoropyrrolidine-2-carboxylic acid?
The molecular weight of 4-Fluoropyrrolidine-2-carboxylic acid is 133.05 g/mol.
Where can I buy 4-Fluoropyrrolidine-2-carboxylic acid?
You can request a quote for 4-Fluoropyrrolidine-2-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Fluoropyrrolidine-2-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 4-Fluoropyrrolidine-2-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.