4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile
TL;DR: 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile (CAS 499117-47-4) is a chemical compound with molecular formula C19H14FN3O2S and molecular weight 367.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile
Also Known As: BAS 06900330, 4-amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile, 4-amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)-3-thiophenecarbonitrile, AM-807/12740226, 4-amino-2-((2-fluorophenyl)amino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile
| Molecular Formula | C19H14FN3O2S |
|---|---|
| Molecular Weight | 367.08 g/mol |
| LogP | 4.32428 |
| Topological Polar Surface Area | 88.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 367.07907 |
| Heavy Atoms | 26 |
| Complexity | 1006.61395 |
Chemical Identifiers
| CAS Number | 499117-47-4 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C(=O)C2=C(C(=C(S2)NC3=CC=CC=C3F)C#N)N |
Product Overview
4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile (CAS 499117-47-4), with molecular formula C19H14FN3O2S and molecular weight 367.08 g/mol. IUPAC: 4-amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile.
Chemical Property Profile of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile
Property Insights of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile
The XLogP value of 4.32428 indicates that 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.14 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile. Following Lipinski's Rule of Five, 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile?
The CAS number of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile is 499117-47-4.
What is the molecular formula of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile?
The molecular formula of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile is C19H14FN3O2S.
What is the molecular weight of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile?
The molecular weight of 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile is 367.08 g/mol.
Where can I buy 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile?
You can request a quote for 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 4-Amino-2-(2-fluoroanilino)-5-(4-methoxybenzoyl)thiophene-3-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.