Azaclorzine structure

Azaclorzine

TL;DR: Azaclorzine (CAS 49864-70-2) is a chemical compound with molecular formula C22H24ClN3OS and molecular weight 413.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-1-(2-chlorophenothiazin-10-yl)propan-1-one

Also Known As: Azaclorzine, Azaclorzina, Azachlorzine, Azaclorzinum, Azaclorzine [INN]

CAS: 49864-70-2
Molecular Formula C22H24ClN3OS
Molecular Weight 413.13 g/mol
LogP 4.0
Topological Polar Surface Area 52.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 413.13287
Heavy Atoms 28
Complexity 578.0

Chemical Identifiers

CAS Number 49864-70-2
SMILES C1CC2CN(CCN2C1)CCC(=O)N3C4=CC=CC=C4SC5=C3C=C(C=C5)Cl
InChIKey ZQTOZLYOIRKCPL-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (31 patents)

Product Overview

Azaclorzine (CAS 49864-70-2), with molecular formula C22H24ClN3OS and molecular weight 413.13 g/mol. IUPAC: 3-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-1-(2-chlorophenothiazin-10-yl)propan-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Azaclorzine

XLogP
4.0
TPSA (Topological Polar Surface Area)
52.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
28
Complexity
578.0
Exact Mass
413.13287
Monoisotopic Mass
413.13287
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Azaclorzine

The XLogP value of 4.0 indicates that Azaclorzine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.1 Ų, Azaclorzine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Azaclorzine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Azaclorzine?

The CAS number of Azaclorzine is 49864-70-2.

What is the molecular formula of Azaclorzine?

The molecular formula of Azaclorzine is C22H24ClN3OS.

What is the molecular weight of Azaclorzine?

The molecular weight of Azaclorzine is 413.13 g/mol.

Where can I buy Azaclorzine?

You can request a quote for Azaclorzine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Azaclorzine?

Yes, KEHONG BIO provides custom synthesis services for Azaclorzine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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