geneticin
TL;DR: geneticin (CAS 49863-47-0) is a chemical compound with molecular formula C20H40N4O10 and molecular weight 496.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
Also Known As: geneticin, antibiotic G 418, antibiotic G-418, G418, G 418
| Molecular Formula | C20H40N4O10 |
|---|---|
| Molecular Weight | 496.27 g/mol |
| LogP | -5.613 |
| Topological Polar Surface Area | 248.39 Ų |
| Hydrogen Bond Donors | 10 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 496.27444 |
| Heavy Atoms | 34 |
| Complexity | 675.26544 |
Chemical Identifiers
| CAS Number | 49863-47-0 |
|---|---|
| SMILES | CC([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)O)O)O |
Product Overview
geneticin (CAS 49863-47-0), with molecular formula C20H40N4O10 and molecular weight 496.27 g/mol. IUPAC: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol.
Chemical Property Profile of geneticin
Property Insights of geneticin
The XLogP value of -5.613 indicates that geneticin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 248.39 Ų indicates high polarity, suggesting geneticin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, geneticin has 10 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of geneticin?
The CAS number of geneticin is 49863-47-0.
What is the molecular formula of geneticin?
The molecular formula of geneticin is C20H40N4O10.
What is the molecular weight of geneticin?
The molecular weight of geneticin is 496.27 g/mol.
Where can I buy geneticin?
You can request a quote for geneticin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for geneticin?
Yes, KEHONG BIO provides custom synthesis services for geneticin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.