N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
TL;DR: N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide (CAS 498570-75-5) is a chemical compound with molecular formula C21H15ClN2O2S and molecular weight 394.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-chloro-2-methoxyphenyl)-2-thiophen-2-ylquinoline-4-carboxamide
Also Known As: DivK1c_005706, CDS1_004666, BIM-0030173.P001, N-(5-chloro-2-methoxyphenyl)-2-thiophen-2-ylquinoline-4-carboxamide, AE-848/11736079
| Molecular Formula | C21H15ClN2O2S |
|---|---|
| Molecular Weight | 394.05 g/mol |
| LogP | 5.8776 |
| Topological Polar Surface Area | 51.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 394.0543 |
| Heavy Atoms | 27 |
| Complexity | 1126.4519 |
Chemical Identifiers
| CAS Number | 498570-75-5 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CS4 |
Product Overview
N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide (CAS 498570-75-5), with molecular formula C21H15ClN2O2S and molecular weight 394.05 g/mol. IUPAC: N-(5-chloro-2-methoxyphenyl)-2-thiophen-2-ylquinoline-4-carboxamide.
Chemical Property Profile of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
Property Insights of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
The XLogP value of 5.8776 indicates that N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.22 Ų, N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The CAS number of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is 498570-75-5.
What is the molecular formula of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The molecular formula of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is C21H15ClN2O2S.
What is the molecular weight of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The molecular weight of N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is 394.05 g/mol.
Where can I buy N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
You can request a quote for N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-chloro-2-methoxyphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.