4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one
TL;DR: 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 498570-28-8) is a chemical compound with molecular formula C26H20FNO3 and molecular weight 413.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-fluorophenyl)-4-hydroxy-1-(4-methylphenyl)-3-[(E)-3-phenylprop-2-enoyl]-2H-pyrrol-5-one
Also Known As: 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one, (4E)-5-(4-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-(4-methylphenyl)pyrrolidine-2,3-dione, 2-(4-fluorophenyl)-4-hydroxy-1-(4-methylphenyl)-3-[(E)-3-phenylprop-2-enoyl]-2H-pyrrol-5-one
| Molecular Formula | C26H20FNO3 |
|---|---|
| Molecular Weight | 413.14 g/mol |
| LogP | 5.31662 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 413.14273 |
| Heavy Atoms | 31 |
| Complexity | 1179.5864 |
Chemical Identifiers
| CAS Number | 498570-28-8 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(C(=C(C2=O)O)C(=O)/C=C/C3=CC=CC=C3)C4=CC=C(C=C4)F |
Product Overview
4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 498570-28-8), with molecular formula C26H20FNO3 and molecular weight 413.14 g/mol. IUPAC: 2-(4-fluorophenyl)-4-hydroxy-1-(4-methylphenyl)-3-[(E)-3-phenylprop-2-enoyl]-2H-pyrrol-5-one.
Chemical Property Profile of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one
Property Insights of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one
The XLogP value of 5.31662 indicates that 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one is 498570-28-8.
What is the molecular formula of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one is C26H20FNO3.
What is the molecular weight of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one is 413.14 g/mol.
Where can I buy 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-cinnamoyl-5-(4-fluorophenyl)-3-hydroxy-1-(p-tolyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.