![2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine structure](/static/products/498/498537-02-3.png)
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine
概要：2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine（CAS 498537-02-3）是一种化学化合物，分子式为C23H29N5O2S，分子量为439.20 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
4,4-dimethyl-N-(oxolan-2-ylmethyl)-8-pyrrolidin-1-yl-5-oxa-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),8,12(17),13,15-hexaen-13-amine
又称：2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine, 2,2-dimethyl-5-(pyrrolidin-1-yl)-N-(tetrahydrofuran-2-ylmethyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine
| 分子式 | C23H29N5O2S |
|---|---|
| 分子量 | 439.20 g/mol |
| LogP | 4.2819 |
| 拓扑极性表面积 | 72.4 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 8 |
| 可旋转键数 | 4 |
| 精确质量 | 439.2042 |
| 重原子数 | 31 |
| 复杂度 | 1132.1398 |
化学标识符
| CAS 编号 | 498537-02-3 |
|---|---|
| SMILES | CC1(CC2=C(CO1)C(=NC3=C2C4=C(S3)C(=NC=N4)NCC5CCCO5)N6CCCC6)C |
产品概述
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine（CAS 498537-02-3），分子式为C23H29N5O2S，分子量为439.20 g/mol。IUPAC名：4,4-dimethyl-N-(oxolan-2-ylmethyl)-8-pyrrolidin-1-yl-5-oxa-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),8,12(17),13,15-hexaen-13-amine。
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine化学性质概览
属性洞察：2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的XLogP值为4.2819，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为72.4 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine有1个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的CAS号是多少？
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的CAS号为498537-02-3。
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的分子式是什么？
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的分子式为C23H29N5O2S。
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的分子量是多少？
2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的分子量为439.20 g/mol。
在哪里可以购买2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine？
您可以直接向科弘生物询价2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine的定制合成服务？
是的，科弘生物提供2,2-dimethyl-5-(pyrrolidin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)-2,4-dihydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。