![3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE structure](/static/products/4985/498536-89-3.webp)
3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
TL;DR: 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE (CAS 498536-89-3) is a chemical compound with molecular formula C26H27N5O3S2 and molecular weight 521.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[[2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-3-propan-2-yl-2-sulfanylidene-1,3-thiazolidin-4-one
Also Known As: 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, (Z)-3-isopropyl-5-((2-(4-(4-methoxyphenyl)piperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)-2-thioxothiazolidin-4-one, (5Z)-5-({2-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}METHYLIDENE)-3-(PROPAN-2-YL)-2-SULFANYLIDENE-1,3-THIAZOLIDIN-4-ONE, (5Z)-5-[[2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-3-propan-2-yl-2-sulfanylidene-1,3-thiazolidin-4-one, 2-[4-(4-methoxyphenyl)piperazin-1-yl]-3-{(Z)-[4-oxo-3-(propan-2-yl)-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}-4H-pyrido[1,2-a]pyrimidin-4-one
| Molecular Formula | C26H27N5O3S2 |
|---|---|
| Molecular Weight | 521.16 g/mol |
| LogP | 3.6393 |
| Topological Polar Surface Area | 70.39 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 521.1555 |
| Heavy Atoms | 36 |
| Complexity | 1409.342 |
Chemical Identifiers
| CAS Number | 498536-89-3 |
|---|---|
| SMILES | CC(C)N1C(=O)/C(=C/C2=C(N=C3C=CC=CN3C2=O)N4CCN(CC4)C5=CC=C(C=C5)OC)/SC1=S |
Product Overview
3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE (CAS 498536-89-3), with molecular formula C26H27N5O3S2 and molecular weight 521.16 g/mol. IUPAC: (5Z)-5-[[2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidin-3-yl]methylidene]-3-propan-2-yl-2-sulfanylidene-1,3-thiazolidin-4-one.
Chemical Property Profile of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
Property Insights of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
The XLogP value of 3.6393 indicates that 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.39 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE. Following Lipinski's Rule of Five, 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The CAS number of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is 498536-89-3.
What is the molecular formula of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The molecular formula of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is C26H27N5O3S2.
What is the molecular weight of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
The molecular weight of 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE is 521.16 g/mol.
Where can I buy 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
You can request a quote for 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE?
Yes, KEHONG BIO provides custom synthesis services for 3-[(Z)-(3-ISOPROPYL-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.