![1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide structure](/static/products/4979/497928-69-5.webp)
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide
TL;DR: 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide (CAS 497928-69-5) is a chemical compound with molecular formula C12H13ClF3N3O and molecular weight 307.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperidine-4-carboxamide
Also Known As: 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide, Bionet2_000031, 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxamide, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-piperidine-4-carboxamide, A3971/0169283
| Molecular Formula | C12H13ClF3N3O |
|---|---|
| Molecular Weight | 307.07 g/mol |
| LogP | 2.4555 |
| Topological Polar Surface Area | 59.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 307.06992 |
| Heavy Atoms | 20 |
| Complexity | 513.1593 |
Chemical Identifiers
| CAS Number | 497928-69-5 |
|---|---|
| SMILES | C1CN(CCC1C(=O)N)C2=C(C=C(C=N2)C(F)(F)F)Cl |
Product Overview
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide (CAS 497928-69-5), with molecular formula C12H13ClF3N3O and molecular weight 307.07 g/mol. IUPAC: 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperidine-4-carboxamide.
Chemical Property Profile of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide
Property Insights of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide
The XLogP value of 2.4555 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide. With a topological polar surface area (TPSA) of 59.22 Ų, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide?
The CAS number of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide is 497928-69-5.
What is the molecular formula of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide?
The molecular formula of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide is C12H13ClF3N3O.
What is the molecular weight of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide?
The molecular weight of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide is 307.07 g/mol.
Where can I buy 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide?
You can request a quote for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.