(E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide
TL;DR: (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide (CAS 497867-50-2) is a chemical compound with molecular formula C18H12F3N3O2 and molecular weight 359.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]pyridine-2-carboxamide
Also Known As: (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide, N'-[(E)-{5-[3-(trifluoromethyl)phenyl]furan-2-yl}methylidene]pyridine-2-carbohydrazide, N-[(E)-[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]pyridine-2-carboxamide
| Molecular Formula | C18H12F3N3O2 |
|---|---|
| Molecular Weight | 359.09 g/mol |
| LogP | 4.1243 |
| Topological Polar Surface Area | 67.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 359.08817 |
| Heavy Atoms | 26 |
| Complexity | 934.1093 |
Chemical Identifiers
| CAS Number | 497867-50-2 |
|---|---|
| SMILES | C1=CC=NC(=C1)C(=O)N/N=C/C2=CC=C(O2)C3=CC(=CC=C3)C(F)(F)F |
Product Overview
(E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide (CAS 497867-50-2), with molecular formula C18H12F3N3O2 and molecular weight 359.09 g/mol. IUPAC: N-[(E)-[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]pyridine-2-carboxamide.
Chemical Property Profile of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide
Property Insights of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide
The XLogP value of 4.1243 indicates that (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.49 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide. Following Lipinski's Rule of Five, (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide?
The CAS number of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide is 497867-50-2.
What is the molecular formula of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide?
The molecular formula of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide is C18H12F3N3O2.
What is the molecular weight of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide?
The molecular weight of (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide is 359.09 g/mol.
Where can I buy (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide?
You can request a quote for (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-((5-(3-(trifluoromethyl)phenyl)furan-2-yl)methylene)picolinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.