![(Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one structure](/static/products/497/497867-22-8.png)
(Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
TL;DR: (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one (CAS 497867-22-8) is a chemical compound with molecular formula C20H17N3O2S and molecular weight 363.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6Z)-6-[(4-ethoxyphenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one
Also Known As: (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one, (6Z)-6-(4-ethoxybenzylidene)-3-(2-methylphenyl)[1,3]thiazolo[2,3-c][1,2,4]triazol-5(6H)-one, (6Z)-6-[(4-ethoxyphenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one
| Molecular Formula | C20H17N3O2S |
|---|---|
| Molecular Weight | 363.10 g/mol |
| LogP | 3.07282 |
| Topological Polar Surface Area | 56.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 363.10416 |
| Heavy Atoms | 26 |
| Complexity | 1176.2112 |
Chemical Identifiers
| CAS Number | 497867-22-8 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)/C=C\2/C(=O)N3C(=NN=C3S2)C4=CC=CC=C4C |
Product Overview
(Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one (CAS 497867-22-8), with molecular formula C20H17N3O2S and molecular weight 363.10 g/mol. IUPAC: (6Z)-6-[(4-ethoxyphenyl)methylidene]-3-(2-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one.
Chemical Property Profile of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
Property Insights of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one
The XLogP value of 3.07282 indicates that (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.49 Ų, (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The CAS number of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is 497867-22-8.
What is the molecular formula of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The molecular formula of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is C20H17N3O2S.
What is the molecular weight of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
The molecular weight of (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one is 363.10 g/mol.
Where can I buy (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
You can request a quote for (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-6-(4-ethoxybenzylidene)-3-(o-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.