2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide
TL;DR: 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide (CAS 497864-83-2) is a chemical compound with molecular formula C22H18Cl2N4OS2 and molecular weight 488.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(3-cyano-6-methyl-4-thiophen-3-yl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)sulfanyl]-N-(2,6-dichlorophenyl)acetamide
Also Known As: 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide, 2-[(3-cyano-6-methyl-4-thiophen-3-yl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)sulfanyl]-N-(2,6-dichlorophenyl)acetamide, 2-{[3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}-N-(2,6-dichlorophenyl)acetamide
| Molecular Formula | C22H18Cl2N4OS2 |
|---|---|
| Molecular Weight | 488.03 g/mol |
| LogP | 5.70728 |
| Topological Polar Surface Area | 69.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 488.0299 |
| Heavy Atoms | 31 |
| Complexity | 1154.9894 |
Chemical Identifiers
| CAS Number | 497864-83-2 |
|---|---|
| SMILES | CN1CCC2=C(C1)C(=C(C(=N2)SCC(=O)NC3=C(C=CC=C3Cl)Cl)C#N)C4=CSC=C4 |
Product Overview
2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide (CAS 497864-83-2), with molecular formula C22H18Cl2N4OS2 and molecular weight 488.03 g/mol. IUPAC: 2-[(3-cyano-6-methyl-4-thiophen-3-yl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)sulfanyl]-N-(2,6-dichlorophenyl)acetamide.
Chemical Property Profile of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide
Property Insights of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide
The XLogP value of 5.70728 indicates that 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 69.02 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide. Following Lipinski's Rule of Five, 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide?
The CAS number of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide is 497864-83-2.
What is the molecular formula of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide?
The molecular formula of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide is C22H18Cl2N4OS2.
What is the molecular weight of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide?
The molecular weight of 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide is 488.03 g/mol.
Where can I buy 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide?
You can request a quote for 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.