![4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione structure](/static/products/497/497245-12-2.png)
4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
TL;DR: 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione (CAS 497245-12-2) is a chemical compound with molecular formula C20H23N5S and molecular weight 365.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
Also Known As: 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione, (E)-4-((4-(diethylamino)benzylidene)amino)-5-(o-tolyl)-4H-1,2,4-triazole-3-thiol, 4-((4-(DIETHYLAMINO)BENZYLIDENE)AMINO)-5-(2-METHYL-PH)-4H-1,2,4-TRIAZOLE-3-THIOL, 4-({(E)-[4-(diethylamino)phenyl]methylidene}amino)-5-(2-methylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione, 4-{(1E)-2-[4-(diethylamino)phenyl]-1-azavinyl}-5-(2-methylphenyl)-1,2,4-triazo le-3-thiol
| Molecular Formula | C20H23N5S |
|---|---|
| Molecular Weight | 365.17 g/mol |
| LogP | 4.64451 |
| Topological Polar Surface Area | 49.21 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 365.16742 |
| Heavy Atoms | 26 |
| Complexity | 948.83295 |
Chemical Identifiers
| CAS Number | 497245-12-2 |
|---|---|
| SMILES | CCN(CC)C1=CC=C(C=C1)/C=N/N2C(=NNC2=S)C3=CC=CC=C3C |
Product Overview
4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione (CAS 497245-12-2), with molecular formula C20H23N5S and molecular weight 365.17 g/mol. IUPAC: 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione.
Chemical Property Profile of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
Property Insights of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
The XLogP value of 4.64451 indicates that 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.21 Ų, 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione?
The CAS number of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione is 497245-12-2.
What is the molecular formula of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione?
The molecular formula of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione is C20H23N5S.
What is the molecular weight of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione?
The molecular weight of 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione is 365.17 g/mol.
Where can I buy 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione?
You can request a quote for 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.