![2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide structure](/static/products/497/497230-93-0.png)
2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide
TL;DR: 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide (CAS 497230-93-0) is a chemical compound with molecular formula C26H26N4O4S and molecular weight 490.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[13,13-dimethyl-6-(4-methylphenyl)-7-oxo-12-oxa-2,4,6-triazatricyclo[8.4.0.03,8]tetradeca-1,3(8),4,9-tetraen-5-yl]sulfanyl]-N-(furan-2-ylmethyl)acetamide
Also Known As: 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide, 2-{[8,8-dimethyl-3-(4-methylphenyl)-4-oxo-3,6,8,9-tetrahydro-4H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(furan-2-ylmethyl)acetamide
| Molecular Formula | C26H26N4O4S |
|---|---|
| Molecular Weight | 490.17 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 122.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 490.16748 |
| Heavy Atoms | 35 |
| Complexity | 828.0 |
Chemical Identifiers
| CAS Number | 497230-93-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(=O)C3=C(N=C4CC(OCC4=C3)(C)C)N=C2SCC(=O)NCC5=CC=CO5 |
| InChIKey | AWFIBRMBMOMBSJ-UHFFFAOYSA-N |
Product Overview
2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide (CAS 497230-93-0), with molecular formula C26H26N4O4S and molecular weight 490.17 g/mol. IUPAC: 2-[[13,13-dimethyl-6-(4-methylphenyl)-7-oxo-12-oxa-2,4,6-triazatricyclo[8.4.0.03,8]tetradeca-1,3(8),4,9-tetraen-5-yl]sulfanyl]-N-(furan-2-ylmethyl)acetamide.
Chemical Property Profile of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide
Property Insights of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide
The XLogP value of 3.3 indicates that 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide. Following Lipinski's Rule of Five, 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide?
The CAS number of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide is 497230-93-0.
What is the molecular formula of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide?
The molecular formula of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide is C26H26N4O4S.
What is the molecular weight of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide?
The molecular weight of 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide is 490.17 g/mol.
Where can I buy 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide?
You can request a quote for 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-((8,8-dimethyl-4-oxo-3-(p-tolyl)-4,6,8,9-tetrahydro-3H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-2-yl)thio)-N-(furan-2-ylmethyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.