![(E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide structure](/static/products/497/497168-75-9.png)
(E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide
TL;DR: (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide (CAS 497168-75-9) is a chemical compound with molecular formula C24H22N4O3S2 and molecular weight 478.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-1-(furan-2-yl)ethylideneamino]-2-[(4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide
Also Known As: (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide, N'-[(1E)-1-(furan-2-yl)ethylidene]-2-[(4-oxo-3-phenyl-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetohydrazide, N-((1E)-2-(2-furyl)-1-azaprop-1-enyl)-2-(4-oxo-3-phenyl(3,5,6,7,8-pentahydrobe nzo[b]thiopheno[2,3-d]pyrimidin-2-ylthio))acetamide, N-[(E)-1-(furan-2-yl)ethylideneamino]-2-[(4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide
| Molecular Formula | C24H22N4O3S2 |
|---|---|
| Molecular Weight | 478.11 g/mol |
| LogP | 4.5515 |
| Topological Polar Surface Area | 89.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 478.11334 |
| Heavy Atoms | 33 |
| Complexity | 1388.856 |
Chemical Identifiers
| CAS Number | 497168-75-9 |
|---|---|
| SMILES | C/C(=N\NC(=O)CSC1=NC2=C(C3=C(S2)CCCC3)C(=O)N1C4=CC=CC=C4)/C5=CC=CO5 |
Product Overview
(E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide (CAS 497168-75-9), with molecular formula C24H22N4O3S2 and molecular weight 478.11 g/mol. IUPAC: N-[(E)-1-(furan-2-yl)ethylideneamino]-2-[(4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide.
Chemical Property Profile of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide
Property Insights of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide
The XLogP value of 4.5515 indicates that (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.49 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide. Following Lipinski's Rule of Five, (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide?
The CAS number of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide is 497168-75-9.
What is the molecular formula of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide?
The molecular formula of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide is C24H22N4O3S2.
What is the molecular weight of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide?
The molecular weight of (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide is 478.11 g/mol.
Where can I buy (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide?
You can request a quote for (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(1-(furan-2-yl)ethylidene)-2-((4-oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.