1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline
TL;DR: 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline (CAS 497146-99-3) is a chemical compound with molecular formula C13H11N3O4 and molecular weight 273.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Also Known As: 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, 5-Aminothalidomide, 5'-Pomalidomide, 5-Amino-Thalidomide, Thalidomide-5'-NH2
| Molecular Formula | C13H11N3O4 |
|---|---|
| Molecular Weight | 273.07 g/mol |
| LogP | -0.33 |
| Topological Polar Surface Area | 109.57 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.07495 |
| Heavy Atoms | 20 |
| Complexity | 667.58014 |
Chemical Identifiers
| CAS Number | 497146-99-3 |
|---|---|
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N |
Product Overview
1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline (CAS 497146-99-3), with molecular formula C13H11N3O4 and molecular weight 273.07 g/mol. IUPAC: 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione.
Chemical Property Profile of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline
Property Insights of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline
The XLogP value of -0.33 indicates that 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 109.57 Ų falls within the moderate polarity range, balancing permeability and solubility for 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline. Following Lipinski's Rule of Five, 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline?
The CAS number of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline is 497146-99-3.
What is the molecular formula of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline?
The molecular formula of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline is C13H11N3O4.
What is the molecular weight of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline?
The molecular weight of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline is 273.07 g/mol.
Where can I buy 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline?
You can request a quote for 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline?
Yes, KEHONG BIO provides custom synthesis services for 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.