![4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine structure](/static/products/497/497082-88-9.png)
4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine
TL;DR: 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine (CAS 497082-88-9) is a chemical compound with molecular formula C16H18ClN3S and molecular weight 319.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[4-(4-chlorophenyl)piperazin-1-yl]-1-thiophen-2-ylethanimine
Also Known As: 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine, (E)-4-(4-chlorophenyl)-N-(1-(thiophen-2-yl)ethylidene)piperazin-1-amine, 4-(4-chlorophenyl)-N-[(E)-1-(2-thienyl)ethylidene]-1-piperazinamine
| Molecular Formula | C16H18ClN3S |
|---|---|
| Molecular Weight | 319.09 g/mol |
| LogP | 3.9477 |
| Topological Polar Surface Area | 18.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 319.091 |
| Heavy Atoms | 21 |
| Complexity | 598.96216 |
Chemical Identifiers
| CAS Number | 497082-88-9 |
|---|---|
| SMILES | C/C(=N\N1CCN(CC1)C2=CC=C(C=C2)Cl)/C3=CC=CS3 |
Product Overview
4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine (CAS 497082-88-9), with molecular formula C16H18ClN3S and molecular weight 319.09 g/mol. IUPAC: (E)-N-[4-(4-chlorophenyl)piperazin-1-yl]-1-thiophen-2-ylethanimine.
Chemical Property Profile of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine
Property Insights of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine
The XLogP value of 3.9477 indicates that 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.84 Ų, 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine?
The CAS number of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine is 497082-88-9.
What is the molecular formula of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine?
The molecular formula of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine is C16H18ClN3S.
What is the molecular weight of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine?
The molecular weight of 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine is 319.09 g/mol.
Where can I buy 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine?
You can request a quote for 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-chlorophenyl)-N-[1-(2-thienyl)ethylidene]-1-piperazinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.